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Turner KM, Huntley A, Yardley T, Dawson S, Dawson S (2024) Defining usual care comparators when designing pragmatic trials of complex health interventions: a methodology review. Trials 25, 117. https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-024-07956-7 View
Toews I, Anglemyer A, Nyirenda JL, Alsaid D, Balduzzi S, Grummich K, Schwingshackl L, Bero L (2024) Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials: a meta-epidemiological study. Cochrane Database of Systematic Reviews (1), MR000034. www.cochranelibrary.com/cdsr/doi/10.1002/14651858.MR000034.pub3/full View
Laursen DRT, Nejstgaard CH, Bjørkedal E, Frost AD, Hansen MR, Paludan-Müller AS, Prosenz J, Werner CP, Hróbjartsson A. (2023) Impact of active placebo controls on estimated drug effects in randomised trials: a systematic review of trials with both active placebo and standard placebo. Cochrane Database of Systematic Reviews 3(3):MR000055. View
Faltinsen E, Todorovac A, Staxen Bruun L, Hróbjartsson A, Gluud C, Kongerslev MT, Simonsen E, Storebø OJ (2022) Control interventions in randomised trials among people with mental health disorders. Cochrane Database of Systematic Reviews 4(4):MR000050. View
Hahn RA, Teutsch SM (2021) Saving lives by modifying the process of science: Estimated historical mortality associated with the failure to conduct routine prospective cumulative systematic reviews. American Journal of Biomed Science and Research 14(6):531-534. View
D'Aquila RT, Hughes MD, Johnson VA, Fischl MA, Sommadossi JP, Liou SH, Timpone J, Myers M, Basgoz N, Niu M, Hirsch MS (2021) Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double- blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators. Annals of Internal Medicine 124:1019-1030. View
Horby P, Lim WS, Emberson J, Mafham M, Bell J, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffrey K, Montgomery A, Rowan K, Juszcak E, Baillie JK, Haynes R, Landray MJ, on behalf of the RECOVERY Collaborative Group (2020) Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report. medRχiv. Doi: https://doi.org/10.1101/2020.06.22.20137273 View
Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, Wiselka M, Ustianowski A, Elmahi E, Prudon B, Whitehouse A, Felton T, Williams J, Faccenda J, Underwood J, Baillie JK, Chappell L, Faust SN, Jaki T, Jeffery K, Lim WS, Montgomery A, Rowan K, Tarning J, Watson JA, White NJ, Juszczak E, Haynes R, Landray MJ (2020) Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial. doi: https://doi.org/10.1101/2020.07.15.20151852 View
RECOVERY Trial Team (2020) Randomized Evaluation of COVID019 Therapy (RECOVERY). RECOVERY Central Coordinating Office, Oxford. www.recoverytrial.net View
Pan H, Peto R, Karim QA, Alejandria M, Henao-Restrepo AM, García CH, Kieny MP, Malekzadeh R, Murthy S, Preziosi MP, Reddy S, Periago MR, Sathiyamoorthy V, Røttingen JA, Swaminathan S, WHO Solidarity trial consortium (2020) Repurposed antiviral drugs for COVID-19 –interim WHO SOLIDARITY trial results. MedRxiv. doi: https://doi.org/10.1101/2020.10.15.20209817 View
Moustgaard H, Clayton GL, Jones HE, Boutron I, Jørgensen L, Laursen DRT, Olsen MF, Paludan-Müller A, Ravaud P, Savović J, Sterne JAC, Higgins JPT, Hróbjartsson A (2020) Impact of blinding on estimated treatment effects in randomised clinical trials: meta-epidemiological study. BMJ 368, l6802. View
Janiaud P, Serghiou S, Ioannidis JPA (2019) New clinical trial designs in the era of precision medicine: An overview of definitions, strengths, weaknesses, and current use in oncology. Cancer Treatment Reviews 73:20-30. View
Chalmers I (2017) The evolution of fair tests of treatments over two millennia: a 23 minute audio commentary. Edited by Hamish Chalmers, using unbroadcast recordings made by Freakonomics Radio, with permission. View
Wartolowska KA, Collins GS, Hopewell S, Judge A, Dean BJF, Rombach I, Beard DJ, Carr AJ (2016) Feasibility of surgical randomised controlled trials with a placebo arm: a systematic review. BMJ Open 6: p.e010194. View
Sackett DL (2015) Sackett DL. Interview in 2014 and 2015. Brian Haynes, ed. McMaster University. View
Fretheim A, Zhang F, Ross-Degnan D, Oxman AD, Cheyne H, Foy R, Goodacre S, Herrin J, Kerse N, McKinlay RJ, Wright A, Soumerai SB (2014) A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation. Journal of Clinical Epidemiology 68:324-33. View
Wartolowska K, Judge A, Hopewell S, Collins GS, Dean BJF, Rombach I, Brindley D, Savulescu J, Beard DJ, Carr AJ (2014) Use of placebo controls in the evaluation of surgery: systematic review. BMJ 348:g3253. doi: 10.1136/bmj.g3253. View
Smith V, Clarke M, Devane D, Begley C, Shorter G, Maguire L (2013) SWAT 1: what effects do site visits by the principal investigator have on recruitment in a multicentre randomized trial? Journal of Evidence-Based Medicine 6(3), 136-137 https://onlinelibrary.wiley.com/doi/epdf/10.1111/jebm.12049 View
Begley CG, Ellis LM (2012) Raise standards for preclinical cancer research. Nature 483:531. View
White IR, Carpenter J, Horton NJ (2012) Including all individuals is not enough: lessons for intention-to-treat analysis. Clinical Trials 9:396-407. View
Clarke M, Loudon K (2011) Effects on patients of their healthcare practitioner's or institution's participation in clinical trials: a systematic review. Trials 12:16. View
Bastian H, Glasziou P, Chalmers I (2010) Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? PLoS Medicine 7:e1000326. View
Djulbegovic B, Kumar A, Soares HP, Hozo I, Bepler G, Clarke M, Bennett CL (2008) Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the national cancer institute-sponsored cooperative oncology groups, 1955 to 2006. Archives of Internal Medicine. 168:632-42. View
Perel P, Roberts I, Sena E, Wheble P, Briscoe C, Sandercock S, Macleod M, Mignini LE, Jayaram P, Khan KS (2007) Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ 334:197-200. View
Glasziou P, Chalmers I, Rawlins M, McCulloch P (2007) When are randomised trials unnecessary? Picking signal from noise. BMJ 334: 349-351. View
Alsbirk PH (2004) Strategy for decentralized prevention of angle closure glaucoma in Greenland. International Journal of Circumpolar Health 2004;63 Suppl 2;315-319. View
Jones B, Kenward MG (2003) Design and Analysis of Cross-Over-Trials (2nd Ed). London and USA: Chapman and Hall. View
Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D (2002) Segmented regression analysis of interrupted time series studies in medication use research. Journal of Clinical Pharmacy and Therapeutics 27:299–309. View
Sandercock P, Roberts I (2002) Systematic reviews of animal experiments. Lancet 360:586. DOI:https://doi.org/10.1016/S0140-6736(02)09812-4. View
Stangl D, Berry DA (2000) Meta-Analysis in Medicine and Health Policy. New York: Marcel Dekker, Inc. View
Sutton AJ, Abrams KR, Jones DR, Sheldon T, Song F (2000) Methods for Meta-Analysis in Medical Research. Chichester: Wiley. View
Djulbegovic B, Lacevic M, Cantor A, Fields KK, Bennett CL, Adams JR, Kuderer NM, Lyman GH (2000) The uncertainty principle and industry-sponsored research. Lancet 356:635-638. View
Murray DM (1998) Design and Analysis of Group Randomized Trials. New York: Oxford University Press Inc. View
Waller LA (1997) A note on Harold S Diehl, randomization, and clinical trials. Controlled Clinical Trials 18: 180-183. View
Lindsey JK, Jones B (1996) A model for cross-over trials evaluating therapeutic preferences. Statistics in Medicine 15:443–7. View
Ellis J, Mulligan I, Rowe J, Sackett DL (1995) Inpatient general medicine is evidence based. Lancet 346:407-410. View
Simpson JM, Klar N, Donner A (1995) Accounting for cluster randomization: a review of primary prevention trials, 1990 through 1993. American Journal of Public Health 85:1378-1383. View
Pennington E, Pennington S (1991) Modifying chickenpox. BMJ 303:1614. View
Donner A, Brown KS, Brasher P (1990) A methodological review of non-therapeutic intervention trials employing cluster randomization, 1979-1989. International Journal of Epidemiology 19:795-800. View
O’Rourke K, Detsky AS (1989) Meta-analysis in medical research: strong encouragement for higher quality in individual research efforts. Journal of Clinical Epidemiology 42:1021-24. View
Pocock SJ, Hughes MD (1989) Practical problems in interim analyses, with particular regard to estimation. Control Clinical Trials10 (4 Suppl):209S-221S. View
Jenicek M (1989) Meta-analysis in medicine: where we are and where we want to go. Journal of Clinical Epidemiology 42:35-44. View
Chalmers TC (1988) Data analysis for clinical medicine: the quantitative approach to patient care in gastroenterology. Rome: International University Press. View
Jenicek M (1987) Méta-analyse en médecine. Évaluation et synthèse de l’information clinique et épidémiologique. [Meta-analysis in medicine: evaluation and synthesis of clinical and epidemiological information] St.Hyacinthe and Paris: EDISEM and Maloine Éditeurs. View
Machin D, Campbell MJ (1987) Statistical Tables for the Design of Clinical Trials. Oxford: Blackwell scientific publications. View
Peto J, Eden OB, Lilleyman J, Richards S (1986) Improvement in treatments for children with acute lymphoblastic leukaemia: The Medical Research Council UKALL Trials, 1972-84. Lancet 1:408-411. View
Gracely RH, Dubner R, Deeter WR, Wolskee PJ (1985) Clinicians’ expectations influence placebo analgesia. Lancet 325:43. DOI:https://doi.org/10.1016/S0140-6736(85)90984-5 View
Baskerville JC, Toogood JH, Mazza J, Jennings B. (1984) Clinical trials designed to evaluate therapeutic preferences. Statistics in Medicine; 3:45–55. View
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Chalmers TC, Smith JH, Blackburn B, Silverman B, Schroeder B, Reitman D, Ambroz A (1981) A method for assessing the quality of a randomized control trial. Controlled Clinical Trials 2: 31-49. View
Sackett DL (1979) Bias in analytic research. Journal of Chronic Diseases 32:51-63. View
Farquhar JW (1978) The community-based model of life style intervention trials. American Journal of Epidemiology 108:103-111. View
Bunker JP, Barnes BA, Mosteller F (1977) Costs, risks and benefits of surgery. Oxford: Oxford University Press. View
Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG (1977) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. British Journal of Cancer 35:1-39. PMID 831755. View
Pocock SJ (1977) Randomised clinical trials. BMJ 1:1661. View
Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG (1976) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. British Journal of Cancer 34:585-6. View
Cornfield J (1976) Recent methodological contributions to clinical trials. American Journal of Epidemiology 104:408-421. View
Chalmers TC (1975) Randomization of the first patient. Medical Clinics of North America 59:1035-1038. View
Cochrane AL (1972) Effectiveness and Efficiency: random reflections on health services. London: Nuffield Provincial Hospitals Trust. View
Cornfield J (1971) The University Group Diabetes Program: a further statistical analysis of the mortality findings. JAMA 217:1676-87. View
Chalmers TC, Sebestyen CS, Lee S (1970) Emergency surgical treatment of bleeding peptic ulcer: An analysis of the published data on 21,130 patients. Trans Am Clin Climatol Assoc 82: 188-99. View
Schwartz D, Flamant R, Lellouch J (1970) L’essai thérapeutique chez l‘homme. Paris: Flammarion. View
Chalmers TC (1968) When should randomisation begin? Lancet 1:858. View
Schwartz D, Lellouch J (1967) Explanatory and pragmatic attitudes in therapeutic trials. Journal of Chronic Diseases 20:637-48. View
Schneiderman MA (1966) Therapeutic trials in cancer. Working paper prepared for WHO Expert Committee on Cancer Treatment, Geneva, Switzerland, 9-15 March 1965. WHO/CANC/66.66. View
Bross ID (1966) Spurious effects from an extraneous variable. Journal of Chronic Diseases 19:637-47. View
Pollock TM, Bell JA, Hill AB, Cockburn WC, Cvjetanović B, Evans DG, Kostrzewski J, Schofield FD (1966) Trials of Prophylactic agents for the control of communicable diseases: a guide to their organization and evaluation. Geneva: World Health Organization. View
Campbell DT, Stanley JC (1963) Experimental and quasi-experimental designs for research. Chicago: Rand McNally & Company. View
Mainland D (1963) Elementary medical statistics: 2nd edn. Philadelphia: WB Saunders Co. View
Hill AB (1962) Alfred Watson Memorial Lecture: The Statistician in Medicine. Journal of the Institute of Actuaries 88:178-191. doi:10.1017/S0020268100014980 View
Cochran WG (1961) Designing clinical trials. In: Forster FM, ed. Evaluation of drug therapy. University of Wisconsin Press, pp 71-77. View
McBride WG (1961) Thalidomide and congenital abnormalities. Lancet 2:1358. View
Schwartz D, Flamant R, Lellouch J, Rouquette C (1960) Les essais thérapeutiques cliniques [Controlled clinical trials]. Paris: Masson. View
Hill AB (1960) Controlled clinical trials. Oxford: Blackwell Scientific Publications. View
Zubrod CG, Schneiderman M, Frei E, Brindley C, Gold GL, Shnider B, Oviedo R, Gorman J, Jones R, Jonsson U, Colsky J, Chalmers T, Ferguson B, Dederick M, Holland J, Selawry O, Regelson W, Lasagna L, Owens AH (1960) Appraisal of methods for the study of chemotherapy in man: Comparative therapeutic trial of nitrogen mustard and thiophosphoramide. Journal of Chronic Diseases 11:7-33. View
Mainland D (1960) The use and misuse of statistics in medical publications. Clinical Pharmacology and Therapeutics 1:411-22. View
Waife SO, Shapiro AP (1959) The clinical evaluation of new drugs. New York: Hoeber-Harper. View
Bull JP (1959) The historical development of clinical therapeutic trials. Journal of Chronic Diseases 10:218-248. View
Witts LJ (1959) Medical surveys and clinical trials: some methods and applications of group research in medicine. Oxford: Oxford University Press. View
Oldham PD (1959) Clinical and field trials. Acta Medica Hungarica 14:313-326. View
Doll R (1959) Practical problems of drug trials in clinical practice. Lawrence DR, ed. Quantitative methods in human pharmacology and therapeutics. Oxford: Pergamon Press, pp. 213-221. View
Symposium on Clinical Trials RSM (1958) Report of a meeting held at the Royal Society of Medicine, London on 25th April 1958. View
Kerr DNS, Davidson S (1958) Gastrointestinal intolerance to oral iron preparations. Lancet 2:489-492. View
Cox DR (1958) Planning of experiments. London: Wiley. View
Greiner T, Bross I, Gold H (1957) A method for evaluation of laxative habits in human subjects. Journal of Chronic Diseases 6:244-255. View
Bjerkelund CJ (1957) The effect of long-term treatment with dicoumarol in myocardial infarction. A controlled clinical study. Acta Med Scand Suppl 330:1-212. View
Herdan G (1955) Statistics of Therapeutic Trials. Amsterdam: Elsevier. View
Lasagna L (1955) The controlled clinical trial: theory and practice. Journal of Chronic Diseases 1:353-367. View
Hogben L (1954) The assessment of remedies. Medical Press 232:331-338. View
Gaddum JH (1954) Clinical pharmacology. Proceedings of the Royal Society of Medicine 47:195-204. View
Bickel H, Gerrard J, Hickmans EM. (1953) Influence of phenylalanine intake on phenylketonuria. Lancet 265:812-813. View
Rinzler SH, Travell J, Bakst H, Benjamin ZH, Rosenthal RL, Rosenfeld S, Hirsch BB (1953) Effect of heparin in effort angina. American Journal of Medicine 14:438-447. View
Baker C, Brock RC, Campbell M, Wood P (1952) Valvulotomy for mitral stenosis; a further report on 100 cases. BMJ 1:1043–1055. View
Hill AB (1952) The clinical trial. New England Journal of Medicine 247:113-119. View
Hill AB (1951) The clinical trial. British Medical Bulletin 7:278-282. View
Daniels M (1951) Clinical evaluation of chemotherapy in tuberculosis. British Medical Bulletin 7:320-326. View
Ross OB (1951) The use of controls in medical research. JAMA 145:72-75. View
Powers E, Witmer HL (1951) An experiment in the prevention of delinquency: the Cambridge-Somerville Youth Study. New York: Columbia University Press. View
Baker C, Brock RC, Campbell M (1950) Valvulotomy for mitral stenosis; report of six successful cases. BMJ 1:1283–1293. View
Rinzler SH, Bakst H, Benjamin Z, Bobb AL, Travell J (1950) Failure of alpha tocopherol to influence chest pain in patients with heart disease. Circulation 1:288-293. View
Reid DD (1950) Statistics in clinical research. Annals of the New York Academy of Sciences 52:931-934. View
Editorial (1950) Are statistics necessary? JAMA 143:1260-1261. View
Appelbaum E, Nelson J, Albin MB (1949) The treatment of penumococcic meningitis with penicillin; a study of 125 consecutive cases, with 73% recovery. American Journal of Medicial Science 218:260-4. View
Marshall EK (1949) Clinical therapeutic trial of a new drug. Bulletin of the Johns Hopkins Hospital 85:221-230. View
Christie RV (1948) Penicillin in subacute bacterial endocarditis. BMJ 1:1-4. View
Bell JA (1948) The epidemiological principles and procedures involved in a study of the prophylactic value of an alum-precipated mixture of diphtheria toxoid and pertussis vaccine. Thesis submitted to the School of Hygiene and Public Health of the Johns Hopkins University in conformity with the requirements for the Degree of Doctor of Public Health. View
Farber S, Diamond LK, Mercer RD, Sylvester RF, Wolff JA (1948) Temporary remissions in acute leukaemia in children produced by folic acide antagonist, 4-aminopteroyl-glutamic acid (aminopterin). New England Journal of Medicine 238:787-793. View
Merk R (1948) Die Stickstoffsenfgasbehandlung der Lymphogranulomatose [Nitrogen Mustard Treatment of Lymphogranulomatosis]. Medizinische Klinik 43:629-35. View
Medical Research Council (1948) Streptomycin treatment of tuberculous meningitis. Lancet 1:582-596. View
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Johnstone RDC (1946) Relapsing benign tertian malaria treated with paludrine. Lancet 2:825-826. View
Blalock A, Taussig HB (1945) The surgical treatment of malformations of the heart: In which there is pulmonary stenosis or pulmonary atresia. JAMA 128:189-202. View
Van Winkle W, Herwick RF, Calvery HO, Smith A (1944) Laboratory and clinical appraisal on new drugs. Report of the Council on Pharmacy and Chemistry. JAMA 126:958-961. View
Hinshaw HC, Feldman WH (1944) Evaluation of therapeutic agents in clinical tuberculosis. American Review in Tuberculosis 50:202-213. View
Florey ME, Florey HW (1943) General and local administration of penicillin. Lancet 1:387. View
Pulvertaft RJPV (1943) Local therapy of war wounds: I with Penicillin (article 1 of 2). Lancet 2:341-36 and 379-384 View
Abraham EP, Chain E, Fletcher CM, Gardner AD, Heatley NG, Jennings AM, Florey HW (1941) Further observations on penicillin. Lancet 2:177-189. View
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Gaddum JH (1940) Pharmacology. London: Oxford University Press 378-383. View
Lanman TH, Heyl HL (1939) Empyema in Children. New England Journal of Medicine 221:1003-1009. View
Banks HS (1939) Chemotherapy of meningococcal meningitis. Lancet 2:921-927. View
Bahnsen P, Jacobsen E, Thesleff H (1938) Studien über die Wirkung von beta-phenyl-isopropylaminsulfdat (Mecodrin) auf normale Menschen. [Studies on the effect of beta-phenyl-isopropylaminsulfdat (Mecodrin) on normal volunteers]. Klinische Wochenschrift 17:1074-1078. View
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Bowie FJ (1938) Chemotherapy in gonorrhoea: a preliminary report on the use of 2-(p-aminobenzenesulphonamido)pyridine, M & B 693. BMJ 2:283-284. View
Bullowa JGM (1937) Serum therapy. In: Bullowa JGM. The management of the pneumonias. New York: Oxford University Press, pp 283-298. View
Editorial (1937) Mathematics and medicine. Lancet 1:31. View
Hill AB (1937) Artificial pneumothorax on statistical trial. Lancet 229: 535-536. View
Hill AB (1937) Principles of medical statistics. I. The aim of the statistical method; and General summary and conclusions. Lancet 1:41-43 and 883-885. View
Colebrook L, Purdie AW (1937) Treatment of 106 cases of puerperal fever by sulphanilamide. Lancet 2:1237-1242 & 1291-1294. View
Parrot A, Catanei A, Ambialet R, Clastrier J (1937) Comparative experiments in mass prophylaxis of malaria by means of quinine and synthetic drugs (quinacrine and praequine). Bulletin of the Health Organization of the League of Nations 6:685-765. View
Hill AB (1937) Principles of medical statistics. London: Lancet. View
Riseman JEF, Brown MG (1937) Medicinal treatment of angina pectoris. Archives of Internal Medicine 60:100-118. View
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Robin L, Van-Huan T (1935) Essais comparés de prophylaxie médicamenteuse en région hyperendémique par la praequine et la quinine ou la quinacrine [Comparative trials of anti-malarial drug prophylaxis in a hyperendemic area with præquine, associated with quinine or quinacrine]. Bulletin de la Société de Pathologie exotique 28:650-658. View
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Greenwood M (1924) Is the statistical method of any value in medical research? Lancet 2: 153-158. View
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Chick H, Dalyell EJ, Hume EM, Mackay HMM, Henderson Smith H, Wimberger H (1923) Observations upon the prophylaxis and cure of rickets at the University Kinderklinik, Vienna. In: Medical Research Council. Studies of rickets in Vienna, 1919-22. Special Report Series No. 77. London: Her Majesty's Stationary Office, pp 19-94. View
McCall WA (1923) How to experiment in education. New York: Macmillan. View
Banting FG, Best CH, Collip JB, Campell WR, Fletcher AA (1922) Pancreatic extracts in the treatment of diabetes mellitus. Canadian Medical Association Journal 12: 141 - 146. View
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Marine D, Kimball OP (1920) The prevention of simple goiter in man: fourth paper. Archives of Internal Medicine 25:661-72. View
Acton HW (1920) Researches on the treatment of benign tertian fever. Lancet 1:1257-1261. View
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ALL ARTICLES
Brief histories
Commentaries
Biographies
Personal reflections
Doctoral theses
Chalmers I, Matthews R, Glasziou P, Boutron I, Armitage P† (2023).Analysis of clinical trial by Treatment Allocated or by Treatment Received? Applying ‘the intention-to-treat principle’. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Nylenna, M (2023).Paul Owren, Christopher Bjerkelund and the dawn of controlled trials in Norway. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Glasziou P, Matthews R, Boutron I, Chalmers I, Armitage P† (2023)The differences and overlaps between ‘explanatory’ and ‘pragmatic’ controlled trials: a historical perspective. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Held L, Matthews RAJ (2022).Paradigm lost: Carl Liebermeister and the development of modern medical statistics. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Ritskes-Hoitinga M, Pound P (2022).The role of systematic reviews in identifying the limitations of preclinical animal research, 2000 – 2022. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Podolsky SH (2022).The (Harry) Gold Standard: angina, suggestion, and the path to the “double-blind” test and Clinical Pharmacology. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Senn SJ, Chalmers I (2021).Giving and taking: ethical treatment assignment in controlled trials. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2020)Probabilistic thinking and the evaluation of therapies, 1700-1900. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Marson Smith P, Colquhoun D, Chalmers I (2019).John Henry Gaddum’s 1940 guidance on controlled clinical trials JLL Bulletin: Commentaries on the history of treatment evaluation. View
Johnson A† (2019).Textbooks and other publications on controlled clinical trials, 1948 to 1983. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Toth B (2018).Pioneering controlled trials of treatments for erysipelas and pneumonia in Glasgow, 1936-47. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Weingarten S (2018).Food in Daniel 1:5-16: the first report of a controlled experiment? JLL Bulletin: Commentaries on the history of treatment evaluation. View
Garattini S (2018).Italian controlled trials to assess prevention and treatment of malaria, 1900-1930s. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tognoni G, Franzosi MG, Garattini S (2018).Embedding patient- and public health-oriented research in a national health service: the GISSI experience. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Pormann PE (2018).Concepts of patient groups in 10th-century Iraq and Persia JLL Bulletin: Commentaries on the history of treatment evaluation. View
Bird A (2018).James Jurin and the avoidance of bias in collecting and assessing evidence on the effects of variolation. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Treasure T (2017).Turning blue babies pink: Alfred Blalock’s shunt for Fallot’s Tetralogy. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Donaldson IML (2016).Petrarch’s letter to Boccaccio ‘on the proud and presumptuous behaviour of physicians’. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Lechuga RI, Castro AC (2016).Dramatic effects of control measures on deaths from yellow fever in Havana, Cuba, in the early 1900’s. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Treasure T (2016).Documenting the dramatic effects of operative treatment of mitral stenosis. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Toth B (2015).Why the MRC Therapeutic Trials Committee didn’t introduce controlled clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Burton MJ (2015).Astley Cooper’s dramatically effective treatment of deafness. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2014).Statistics and the British controversy about the effects of Joseph Lister’s system of antisepsis for surgery, 1867-1890. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Gachelin G (2013).The interaction of scientific evidence and politics in debates about preventing malaria in 1925. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Sugiyama Y, Seita A (2013).Kanehiro Takaki and the control of beriberi in the Japanese Navy. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2013).William Cheselden’s 1740 presentation of data on age-specific mortality after lithotomy. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Milne I (2012).Who was James Lind, and what exactly did he achieve? JLL Bulletin: Commentaries on the history of treatment evaluation. View
Vandenbroucke JP (2012).Adolphe Vorderman’s 1897 study on beriberi: an example of scrupulous efforts to avoid bias. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Doyle D (2011).Thomas MacLagan’s 1876 demonstration of the dramatic effects of salicin in rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Maehle A-H (2011).Four early clinical studies to assess the effects of Peruvian bark. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Solis C (2011).Bartolomé Hidalgo de Agüero’s 16th century, evidence-based challenge to the orthodox management of wounds. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Cook H (2010).Testing the effects of Jesuit’s bark in the Chinese Emperor’s court. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Gluud C (2010).Danish contributions to the evaluation of serum therapy for diphtheria in the 1890s. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Morabia A (2010).Edward Jenner’s 1798 report of challenge experiments demonstrating the protective effects of cowpox against smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Opinel A, Gachelin G (2010).French 19th century contributions to the development of treatments for diphtheria. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Slater SD (2010).The discovery of thyroid replacement therapy. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Spain P, Kadan-Lottick N (2010).Observations of unprecedented remissions following novel treatment for acute leukemia in children in 1948. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2010).Towards endocrinology: Theodor Kocher’s 1883 account of the unexpected effects of total ablation of the thyroid. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Adams CE (2009).James Crichton Browne and controlled evaluation of drug treatment for mental illness. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Burch D (2009).Astley Paston Cooper (1768–1841), anatomist, radical, and surgeon. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Dean ME (2009).Comparative evaluation of homeopathy and allopathy within the Parisian hospital system, 1849-51. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Moore W (2009).John Hunter: learning from natural experiments, ‘placebos’, and the state of mind of a patient in the 18th century. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Williams KJ (2009).The introduction of ‘chemotherapy’ using arsphenamine – the first magic bullet. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Agnew RAL (2008).John Forbes FRS (1787-1861). JLL Bulletin: Commentaries on the history of treatment evaluation. View
Jick H (2008).Learning how to control biases in studies to identify adverse effects of drugs: a brief personal history. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Nunn JF (2008).A treatment that has stood the test of time for over three and a half millennia. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Stylianou C, Kelnar C (2008).The introduction of successful treatment of diabetes mellitus with insulin. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Kerr CE, Milne I, Kaptchuk TJ (2007).William Cullen and a missing mind-body link in the early history of placebos. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Louis-Courvoisier M (2007).An 18th century controlled trial prompted by a potential shortage of hospital beds. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Nasser M, Tibi A, Savage-Smith E (2007).Ibn Sina’s Canon of Medicine: 11th century rules for assessing the effects of drugs. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Sinclair L (2007).Recognising, treating and understanding pernicious anaemia. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2007).An early 18th century proposal for improving medicine by tabulating and analysing practice. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Nasser M, Tibi A (2006).Ibn Hindu and the science of medicine. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tibi S (2005).Al-Razi and Islamic medicine in the 9th Century. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Volmink J (2005).The willow as a Hottentot (Khoikhoi) remedy for rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Gøtzsche PC (2004).Niels Finsen’s treatment for lupus vulgaris. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Lee MR (2004).The miracle of St. Alfege’s: discovering a treatment for myaesthenia gravis. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Morabia A (2004).Pierre-Charles-Alexandre Louis and the evaluation of bloodletting. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Sutton G (2004).James Lind aboard Salisbury. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Dean ME (2003).‘An innocent deception’: placebo controls in the St Petersburg homeopathy trial, 1829-30. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Gong Y, Gluud C (2003).Commentary on the Ben Cao Tu Jing (11th century). Atlas of Materia Medica. Song Dynasty (960-1279). JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).John Clark 1780 & 1792: learning from properly kept records. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).John Clark (1744-1805). JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).Withering’s 1785 appeal for caution when reporting on a new medicine. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).James Lind and scurvy: 1747 to 1795. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).James Lind and the evaluation of clinical practice. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).Edward Alanson 1782: responsibility in surgical innovation. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).Edward Alanson (1747-1823). JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).MacLean 1818: comparing like with like and recognising ethical double standards in therapeutic experimentation. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (2003).James Lind at Haslar Hospital 1758-1774: a methodological theorist. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Vandenbroucke JP (2003).Thalidomide: an unanticipated adverse effect. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Armitage P† (2003).Some recollections of the early years of the Medical Research Council (MRC) Statistical Research Unit. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Loudon I (2002).The use of historical controls and concurrent controls to assess the effects of sulphonamides, 1936-1945. JLL Bulletin: Commentaries on the history of treatment evaluation. View
Passmore R† (2001).William Cullen (1710-1790). JLL Bulletin: Commentaries on the history of treatment evaluation. View
Tröhler U (1978).Quantification in British Medicine and Surgery 1750-1830, with special Reference to its Introduction into Therapeutics. Philosophy Thesis, University of London. JLL Bulletin: Commentaries on the history of treatment evaluation. View
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